› 1vj0

X-ray diffraction
2Å resolution

Crystal structure of Alcohol dehydrogenase (TM0436) from Thermotoga maritima at 2.00 A resolution

Released:
DOI: 10.2210/pdb1vj0/pdb
PDB entry 1vj0 coloured by chain, front view.
PDB entry 1vj0 coloured by chain, side view.
PDB entry 1vj0 coloured by chain, top view.
Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
A primary alcohol + NAD(+) = an aldehyde + NADH
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194534 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enoyl reductase (ER) domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 380 amino acids
Theoretical weight: 42.07 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WYR7 (Residues: 1-368; Coverage: 100%)
Gene name: TM_0436
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ZN 8 x ZN
Ligand UNL 4 x UNL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P212121
Unit cell:
a: 92.88Å b: 104.919Å c: 161.617Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.146 0.145 0.194
Expression system: Escherichia coli

Quick links