› 1vjv

X-ray diffraction
1.74Å resolution

Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces cerevisiae at 1.74 A resolution

Released:
DOI: 10.2210/pdb1vjv/pdb
PDB entry 1vjv coloured by chain, front view.
PDB entry 1vjv coloured by chain, side view.
PDB entry 1vjv coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155100 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin carboxyl-terminal hydrolase 6 Chain: A
Molecule details ›
Chain: A
Length: 415 amino acids
Theoretical weight: 48.65 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P43593 (Residues: 97-499; Coverage: 81%)
Gene names: UBP6, YFR010W
Sequence domains: Ubiquitin carboxyl-terminal hydrolase
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 9 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1, APS BEAMLINE 19-BM
Spacegroup: P212121
Unit cell:
a: 49.231Å b: 79.449Å c: 106.339Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.209
Expression system: Escherichia coli

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