› 1vkz

X-ray diffraction
2.3Å resolution

Crystal structure of Phosphoribosylamine--glycine ligase (TM1250) from Thermotoga maritima at 2.30 A resolution

Released:
DOI: 10.2210/pdb1vkz/pdb
PDB entry 1vkz coloured by chain, front view.
PDB entry 1vkz coloured by chain, side view.
PDB entry 1vkz coloured by chain, top view.
Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194754 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoribosylamine--glycine ligase Chains: A, B
Molecule details ›
Chains: A, B
Length: 412 amino acids
Theoretical weight: 46.27 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X0X7 (Residues: 1-400; Coverage: 100%)
Gene names: TM_1250, purD
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand EDO 1 x EDO
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1, APS BEAMLINE 19-BM
Spacegroup: P21
Unit cell:
a: 63.745Å b: 78.443Å c: 85.018Å
α: 90° β: 95.06° γ: 90°
R-values:
R R work R free
0.216 0.213 0.264
Expression system: Escherichia coli

Quick links