› 1vl2

X-ray diffraction
1.65Å resolution

Crystal structure of Argininosuccinate synthase (TM1780) from Thermotoga maritima at 1.65 A resolution

Released:
DOI: 10.2210/pdb1vl2/pdb
PDB entry 1vl2 coloured by chain, front view.
PDB entry 1vl2 coloured by chain, side view.
PDB entry 1vl2 coloured by chain, top view.
Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194883 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Argininosuccinate synthase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 421 amino acids
Theoretical weight: 47.58 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X2A1 (Residues: 1-409; Coverage: 100%)
Gene names: TM_1780, argG
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P212121
Unit cell:
a: 95.322Å b: 114.906Å c: 149.606Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.209
Expression system: Escherichia coli

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