› 1vpc

Solution NMR

C-TERMINAL DOMAIN (52-96) OF THE HIV-1 REGULATORY PROTEIN VPR, NMR, 1 STRUCTURE

Released:
DOI: 10.2210/pdb1vpc/pdb
PDB entry 1vpc coloured by chain, front view.
PDB entry 1vpc coloured by chain, side view.
PDB entry 1vpc coloured by chain, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions.
Schüler W, Wecker K, de Rocquigny H, Baudat Y, Sire J, Roques BP
J Mol Biol 285 2105-17 (1999)
PMID: 9925788

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180926 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein Vpr Chain: A
Molecule details ›
Chain: A
Length: 45 amino acids
Theoretical weight: 5.26 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: Q73369 (Residues: 52-96; Coverage: 47%)
Gene name: vpr
Sequence domains: VPR/VPX protein
Structure domains: VpR/VpX protein, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DYNAMICAL SIMULATED ANNEALING, MOLECULAR DYNAMICS, ENERGY MINIMIZATION
Expression system: Not provided

Quick links

Citations

18 review citations

Mitochondria: a target for cancer therapy.
Armstrong JS. (2006)
17 more

1 mention without citation

Chemical shift prediction for protein structure calculation and quality assessment using an optimally parameterized force field.
Nielsen et al. (2012)