Function and Biology Details
Reaction catalysed:
D-glycerate + NAD(P)(+) = 2-hydroxy-3-oxopropanoate + NAD(P)H
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- 2-hydroxy-3-oxopropionate reductase
- 3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain
- 6-phosphogluconate dehydrogenase, domain 2
- 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
- 3-hydroxyisobutyrate dehydrogenase-related, conserved site
- 6-phosphogluconate dehydrogenase, NADP-binding
- NAD(P)-binding domain superfamily
- 3-hydroxyisobutyrate dehydrogenase-related
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
2-hydroxy-3-oxopropionate reductase (preferred)
PDBe Complex ID:
PDB-CPX-187265 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-hydroxy-3-oxopropionate reductase
Molecule details ›
Chain: A
Length: 299 amino acids
Theoretical weight: 31.74 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 299 amino acids
Theoretical weight: 31.74 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8ZLV8 (Residues: 1-296; Coverage: 100%)
Sequence domains:
- NAD binding domain of 6-phosphogluconate dehydrogenase
- NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
