› 1vps

X-ray diffraction
1.9Å resolution

POLYOMAVIRUS VP1 PENTAMER COMPLEXED WITH A DISIALYLATED HEXASACCHARIDE

Released:
DOI: 10.2210/pdb1vps/pdb
PDB entry 1vps coloured by chain, front view.
PDB entry 1vps coloured by chain, side view.
PDB entry 1vps coloured by chain, top view.
Source organism: Mus musculus polyomavirus 1
Primary publication:
High-resolution structure of a polyomavirus VP1-oligosaccharide complex: implications for assembly and receptor binding.
Stehle T, Harrison SC
EMBO J 16 5139-48 (1997)
PMID: 9305654

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo pentamer (preferred)
homo decamer
Assembly name:
PDBe Complex ID:
PDB-CPX-155915 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Capsid protein VP1 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 289 amino acids
Theoretical weight: 32.09 KDa
Source organism: Mus musculus polyomavirus 1
Expression system: Escherichia coli
UniProt:
  • Canonical: P49302 (Residues: 33-321; Coverage: 75%)
Sequence domains: Polyomavirus coat protein
Structure domains: Capsid protein VP1,Polyomavirus

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, GAL, SIA
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P3121
Unit cell:
a: 221.5Å b: 221.5Å c: 99.8Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.177 0.177 0.205
Expression system: Escherichia coli

Quick links

Citations

34 review citations

Virus entry: open sesame.
Marsh et al. (2006)
33 more

16 mentions without citation

Viruses and sialic acids: rules of engagement.
Neu et al. (2011)
15 more