› 1vqz

X-ray diffraction
1.99Å resolution

Crystal structure of a putative lipoate-protein ligase a (sp_1160) from streptococcus pneumoniae tigr4 at 1.99 A resolution

Released:
DOI: 10.2210/pdb1vqz/pdb
PDB entry 1vqz coloured by chain, front view.
PDB entry 1vqz coloured by chain, side view.
PDB entry 1vqz coloured by chain, top view.
Source organism: Streptococcus pneumoniae TIGR4
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
(1a) ATP + (R)-lipoate = lipoyl-AMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101442 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
lipoate--protein ligase Chain: A
Molecule details ›
Chain: A
Length: 341 amino acids
Theoretical weight: 39.48 KDa
Source organism: Streptococcus pneumoniae TIGR4
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H2UQ30 (Residues: 1-329; Coverage: 100%)
Gene name: SP_1160
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand UNL 1 x UNL
Ligand EDO 17 x EDO
1 modified residue:
Ligand MSE 5 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 45.503Å b: 70.28Å c: 113.629Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.159 0.217
Expression system: Escherichia coli

Quick links