Function and Biology Details
Reaction catalysed:
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H(2)O = 1-alkyl-sn-glycero-3-phosphocholine + acetate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Platelet-activating factor acetylhydrolase IB (preferred)
PDBe Complex ID:
PDB-CPX-158918 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Platelet-activating factor acetylhydrolase IB subunit alpha2
Molecule details ›
Chains: A, B, E, F, I, J, M, N, Q, R
Length: 229 amino acids
Theoretical weight: 25.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: GDSL-like Lipase/Acylhydrolase family
Structure domains: SGNH hydrolase
Length: 229 amino acids
Theoretical weight: 25.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P68402 (Residues: 1-229; Coverage: 100%)
Sequence domains: GDSL-like Lipase/Acylhydrolase family
Structure domains: SGNH hydrolase
Platelet-activating factor acetylhydrolase IB subunit beta
Molecule details ›
Chains: C, D, G, H, K, L, O, P, S, T
Length: 410 amino acids
Theoretical weight: 46.79 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Length: 410 amino acids
Theoretical weight: 46.79 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P63005 (Residues: 1-410; Coverage: 100%)
Sequence domains:
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID29
Spacegroup:
P21
Expression systems:
- Escherichia coli BL21(DE3)
- Spodoptera frugiperda
