› 1w2e

X-ray diffraction
2.8Å resolution

The Crystal Structure of the Bacterial Cell Division Protein ZapA

Released:
DOI: 10.2210/pdb1w2e/pdb
PDB entry 1w2e coloured by chain, front view.
PDB entry 1w2e coloured by chain, side view.
PDB entry 1w2e coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
The crystal structure of ZapA and its modulation of FtsZ polymerisation.
Low HH, Moncrieffe MC, Löwe J
J Mol Biol 341 839-52 (2004)
PMID: 15288790

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190938 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell division protein ZapA Chains: A, B
Molecule details ›
Chains: A, B
Length: 104 amino acids
Theoretical weight: 11.81 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HTW3 (Residues: 1-104; Coverage: 100%)
Gene names: PA5227, zapA
Sequence domains: Cell division protein ZapA
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.2
Spacegroup: P41212
Unit cell:
a: 105.96Å b: 105.96Å c: 36.26Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.24 0.289
Expression system: Escherichia coli BL21(DE3)

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Citations

24 review citations

Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Adams et al. (2009)
23 more

2 mentions without citation

Host Defense Peptide-Mimicking Polymers and Polymeric-Brush-Tethered Host Defense Peptides: Recent Developments, Limitations, and Potential Success.
Etayash et al. (2021)
1 more