› 1w2z

X-ray diffraction
2.24Å resolution

PSAO and Xenon

Released:
DOI: 10.2210/pdb1w2z/pdb
PDB entry 1w2z coloured by chain, front view.
PDB entry 1w2z coloured by chain, side view.
PDB entry 1w2z coloured by chain, top view.
Source organism: Pisum sativum
Primary publication:
Using xenon as a probe for dioxygen-binding sites in copper amine oxidases.
Duff AP, Trambaiolo DM, Cohen AE, Ellis PJ, Juda GA, Shepard EM, Langley DB, Dooley DM, Freeman HC, Guss JM
J Mol Biol 344 599-607 (2004)
PMID: 15533431

Function and Biology Details

Reaction catalysed: 
RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174980 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Primary amine oxidase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 649 amino acids
Theoretical weight: 73.8 KDa
Source organism: Pisum sativum
UniProt:
  • Canonical: Q43077 (Residues: 26-674; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

5 bound ligands:
Ligand CU 4 x CU
Ligand MN 4 x MN
Ligand XE 8 x XE
Ligand NAG 8 x NAG
Ligand IOD 176 x IOD
1 modified residue:
Ligand TPQ 4 x TPQ

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 89.507Å b: 196.268Å c: 89.665Å
α: 90° β: 107.46° γ: 90°
R-values:
R R work R free
0.181 0.179 0.224

Quick links

Citations

2 review citations

Molecular Insights Into Lysyl Oxidases in Cartilage Regeneration and Rejuvenation.
Lin et al. (2020)
1 more

4 mentions without citation

Copper active sites in biology.
Solomon et al. (2014)
3 more