› 1w3z

X-ray diffraction
3.2Å resolution

SeMet derivative of BbCRASP-1 from Borrelia Burgdorferi

Released:
DOI: 10.2210/pdb1w3z/pdb
PDB entry 1w3z coloured by chain, front view.
PDB entry 1w3z coloured by chain, side view.
PDB entry 1w3z coloured by chain, top view.
Source organism: Borreliella burgdorferi ZS7
Primary publication:
A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi.
Cordes FS, Roversi P, Kraiczy P, Simon MM, Brade V, Jahraus O, Wallis R, Skerka C, Zipfel PF, Wallich R, Lea SM
Nat Struct Mol Biol 12 276-7 (2005)
PMID: 15711564

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129343 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement regulator-acquiring surface protein 1 (CRASP-1) Chains: A, B
Molecule details ›
Chains: A, B
Length: 181 amino acids
Theoretical weight: 21.57 KDa
Source organism: Borreliella burgdorferi ZS7
Expression system: Escherichia coli
UniProt:
  • Canonical: O50957 (Residues: 70-250; Coverage: 80%)
Gene names: BB_A68, cspA
Sequence domains: Borrelia Bbcrasp-1 domain containing protein
Structure domains: Bbcrasp-1

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P43212
Unit cell:
a: 91.558Å b: 91.558Å c: 146.517Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.239 not available
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Factor H family proteins and human diseases.
Józsi et al. (2008)
5 more

1 mention without citation

Complement Evasion by Lyme Disease Spirochetes.
Skare et al. (2020)