› 1w45

X-ray diffraction
2.51Å resolution

The 2.5 Angstroem structure of the K16A mutant of annexin A8, which has an intact N-terminus.

Released:
DOI: 10.2210/pdb1w45/pdb
PDB entry 1w45 coloured by chain, front view.
PDB entry 1w45 coloured by chain, side view.
PDB entry 1w45 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The crystal structure of annexin A8 is similar to that of annexin A3.
Réty S, Sopková-de Oliveira Santos J, Dreyfuss L, Blondeau K, Hofbauerová K, Raguénès-Nicol C, Kerboeuf D, Renouard M, Russo-Marie F, Lewit-Bentley A
J Mol Biol 345 1131-9 (2005)
PMID: 15644210

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146819 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin A8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 327 amino acids
Theoretical weight: 36.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P13928 (Residues: 1-327; Coverage: 100%)
Gene names: ANX8, ANXA8
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P1
Unit cell:
a: 49.297Å b: 59.653Å c: 70.788Å
α: 84.42° β: 83.32° γ: 74.1°
R-values:
R R work R free
0.209 0.206 0.269
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

The role of annexins in tumour development and progression.
Mussunoor et al. (2008)
1 more

2 mentions without citation

Spatial arrangement of proteins in planar and curved membranes by PPM 3.0.
Lomize et al. (2022)
1 more