› 1w5b

X-ray diffraction
2.2Å resolution

FtsZ dimer, GTP soak (M. jannaschii)

Released:
DOI: 10.2210/pdb1w5b/pdb
PDB entry 1w5b coloured by chain, front view.
PDB entry 1w5b coloured by chain, side view.
PDB entry 1w5b coloured by chain, top view.
Source organism: Methanocaldococcus jannaschii
Primary publication:
Structural insights into FtsZ protofilament formation.
Oliva MA, Cordell SC, Löwe J
Nat Struct Mol Biol 11 1243-50 (2004)
PMID: 15558053

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176475 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell division protein FtsZ 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 364 amino acids
Theoretical weight: 38.97 KDa
Source organism: Methanocaldococcus jannaschii
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q57816 (Residues: 1-364; Coverage: 100%)
Gene names: MJ0370, ftsZ1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand GTP 2 x GTP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21
Unit cell:
a: 70.303Å b: 55.203Å c: 88.129Å
α: 90° β: 90.97° γ: 90°
R-values:
R R work R free
0.209 0.209 0.259
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

37 review citations

Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Adams et al. (2009)
36 more

8 mentions without citation

Targeting Bacterial Cell Division: A Binding Site-Centered Approach to the Most Promising Inhibitors of the Essential Protein FtsZ.
Casiraghi et al. (2020)
7 more