› 1w8j

X-ray diffraction
2.7Å resolution

Crystal Structure Of Myosin V Motor Domain - Nucleotide-Free

Released:
DOI: 10.2210/pdb1w8j/pdb
PDB entry 1w8j coloured by chain, front view.
PDB entry 1w8j coloured by chain, side view.
PDB entry 1w8j coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Three myosin V structures delineate essential features of chemo-mechanical transduction.
Coureux PD, Sweeney HL, Houdusse A
EMBO J 23 4527-37 (2004)
PMID: 15510214

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169719 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Unconventional myosin-Va Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 766 amino acids
Theoretical weight: 88.04 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q02440 (Residues: 1-766; Coverage: 42%)
Gene name: MYO5A
Sequence domains: Myosin head (motor domain)

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P212121
Unit cell:
a: 134.476Å b: 162.308Å c: 174.696Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.257 0.255 0.308
Expression system: Spodoptera frugiperda

Quick links

Citations

22 review citations

Structural and functional insights into the Myosin motor mechanism.
Sweeney et al. (2010)
21 more

11 mentions without citation

Force generation by kinesin and myosin cytoskeletal motor proteins.
Kull et al. (2013)
10 more