› 1w9n

Solution NMR

Isolation and characterization of epilancin 15X, a novel antibiotic from a clinical strain of Staphylococcus epidermidis

Released:
DOI: 10.2210/pdb1w9n/pdb
PDB entry 1w9n coloured by chain, ensemble of 20 models, front view.
PDB entry 1w9n coloured by chain, ensemble of 20 models, side view.
PDB entry 1w9n coloured by chain, ensemble of 20 models, top view.
Source organism: Staphylococcus epidermidis
Primary publication:
Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis.
Ekkelenkamp MB, Hanssen M, Danny Hsu ST, de Jong A, Milatovic D, Verhoef J, van Nuland NA
FEBS Lett 579 1917-22 (2005)
PMID: 15792796

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160959 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lantibiotic epilancin 15X Chain: A
Molecule details ›
Chain: A
Length: 31 amino acids
Theoretical weight: 3.19 KDa
Source organism: Staphylococcus epidermidis
UniProt:
  • Canonical: P86047 (Residues: 26-55; Coverage: 55%)
Gene name: elxA
Sequence domains: Type A lantibiotic family

Ligands and Environments

No bound ligands
3 modified residues:
Ligand DHA 1 x DHA
Ligand DBU 3 x DBU
Ligand DAL 1 x DAL

Experiments and Validation Details

Entry percentile scores
Refinement method: ARIA

Quick links

Citations

22 review citations

Skin microbiota: a source of disease or defence?
Cogen et al. (2008)
21 more