› 1wc7

X-ray diffraction
2.33Å resolution

FAB FRAGMENT OF PLP-DEPENDENT CATALYTIC ANTIBODY 15A9 IN COMPLEX WITH PHOSPHOPYRIDOXYL-L-ALANINE

Released:
DOI: 10.2210/pdb1wc7/pdb
PDB entry 1wc7 coloured by chain, front view.
PDB entry 1wc7 coloured by chain, side view.
PDB entry 1wc7 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure of a pseudomerohedrally twinned monoclinic crystal form of a pyridoxal phosphate-dependent catalytic antibody.
Golinelli-Pimpaneau B
Acta Crystallogr D Biol Crystallogr 61 472-6 (2005)
PMID: 15805602

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213107 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
FAB FRAGMENT OF CATALYTIC ANTIBODY 15A9, LIGHT CHAIN Chains: A, L
Molecule details ›
Chains: A, L
Length: 213 amino acids
Theoretical weight: 23.36 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins
FAB FRAGMENT OF CATALYTIC ANTIBODY 15A9, HEAVY CHAIN Chains: B, H
Molecule details ›
Chains: B, H
Length: 226 amino acids
Theoretical weight: 24.5 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand IOD 5 x IOD
Ligand PP3 1 x PP3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P21
Unit cell:
a: 63.476Å b: 81.691Å c: 79.33Å
α: 90° β: 89.98° γ: 90°
R-values:
R R work R free
0.223 not available 0.309
Expression system: Mus musculus

Quick links

Citations

4 citation in other articles

The structure and evolution of the murine inhibitor of carbonic anhydrase: a member of the transferrin superfamily.
Eckenroth et al. (2010)
3 more

3 mentions without citation

Toward high-resolution homology modeling of antibody Fv regions and application to antibody-antigen docking.
Sivasubramanian et al. (2009)
2 more