› 1wh4

Solution NMR

Solution structure of the DEATH domain of Interleukin-1 receptor-associated kinase4 (IRAK4) from Mus musculus

Released:
DOI: 10.2210/pdb1wh4/pdb
PDB entry 1wh4 coloured by chain, ensemble of 20 models, front view.
PDB entry 1wh4 coloured by chain, ensemble of 20 models, side view.
PDB entry 1wh4 coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Entry authors: Nameki N, Tomizawa T, Koshiba S, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185898 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-1 receptor-associated kinase 4 Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 13.77 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q8R4K2 (Residues: 1-114; Coverage: 25%)
Gene name: Irak4
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrained molecular dynamics
Expression system: Not provided

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