› 1wht

X-ray diffraction
2Å resolution

STRUCTURE OF THE COMPLEX OF L-BENZYLSUCCINATE WITH WHEAT SERINE CARBOXYPEPTIDASE II AT 2.0 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1wht/pdb
PDB entry 1wht coloured by chain, front view.
PDB entry 1wht coloured by chain, side view.
PDB entry 1wht coloured by chain, top view.
Source organism: Triticum aestivum
Primary publication:
Structure of the complex of L-benzylsuccinate with wheat serine carboxypeptidase II at 2.0-A resolution.
Bullock TL, Branchaud B, Remington SJ
Biochemistry 33 11127-34 (1994)
PMID: 7727364

Function and Biology Details

Reaction catalysed: 
Preferential release of a C-terminal arginine or lysine residue.
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140385 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Serine carboxypeptidase 2 chain A Chain: A
Molecule details ›
Chain: A
Length: 256 amino acids
Theoretical weight: 28.49 KDa
Source organism: Triticum aestivum
Expression system: Not provided
UniProt:
  • Canonical: P08819 (Residues: 5-260; Coverage: 58%)
Gene name: CBP2
Sequence domains: Serine carboxypeptidase
Structure domains: alpha/beta hydrolase
Serine carboxypeptidase 2 chain B Chain: B
Molecule details ›
Chain: B
Length: 153 amino acids
Theoretical weight: 17.32 KDa
Source organism: Triticum aestivum
Expression system: Not provided
UniProt:
  • Canonical: P08819 (Residues: 287-439; Coverage: 35%)
Gene name: CBP2
Sequence domains: Serine carboxypeptidase
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC, NDG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand NAG 1 x NAG
Ligand BZS 1 x BZS
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P41212
Unit cell:
a: 95.5Å b: 95.5Å c: 208.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 not available not available
Expression system: Not provided

Quick links

Citations

2 review citations

Peptidase inhibitors in the MEROPS database.
Rawlings ND. (2010)
1 more

5 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
4 more