› 1wi0

Solution NMR

Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)

Released:
DOI: 10.2210/pdb1wi0/pdb
PDB entry 1wi0 coloured by chain, ensemble of 20 models, front view.
PDB entry 1wi0 coloured by chain, ensemble of 20 models, side view.
PDB entry 1wi0 coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Entry authors: Yoneyama M, Hayashi F, Tochio N, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194411 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dual specificity mitogen-activated protein kinase kinase 5 Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.41 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q9WVS7 (Residues: 8-107; Coverage: 22%)
Gene names: Map2k5, Mek5, Mkk5, Prkmk5
Sequence domains: PB1 domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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