› 1wm4

Solution NMR

Solution structure of mouse coactosin, an actin filament binding protein

Released:
DOI: 10.2210/pdb1wm4/pdb
PDB entry 1wm4 coloured by chain, ensemble of 15 models, front view.
PDB entry 1wm4 coloured by chain, ensemble of 15 models, side view.
PDB entry 1wm4 coloured by chain, ensemble of 15 models, top view.
Source organism: Mus musculus
Primary publication:
Solution structure of coactosin reveals structural homology to ADF/cofilin family proteins.
Hellman M, Paavilainen VO, Naumanen P, Lappalainen P, Annila A, Permi P
FEBS Lett 576 91-6 (2004)
PMID: 15474017

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coactosin-like protein Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 15.96 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9CQI6 (Residues: 1-142; Coverage: 100%)
Gene names: Clp, Cotl1
Sequence domains: Cofilin/tropomyosin-type actin-binding protein
Structure domains: Severin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli BL21(DE3)

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Citations

2 review citations

Actin-depolymerizing factor homology domain: a conserved fold performing diverse roles in cytoskeletal dynamics.
Poukkula et al. (2011)
1 more

2 mentions without citation

Structural basis and evolutionary origin of actin filament capping by twinfilin.
Paavilainen et al. (2007)
1 more