› 1wmg

X-ray diffraction
2.1Å resolution

Crystal structure of the UNC5H2 death domain

Released:
DOI: 10.2210/pdb1wmg/pdb
PDB entry 1wmg coloured by chain, front view.
PDB entry 1wmg coloured by chain, side view.
PDB entry 1wmg coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure of the UNC5H2 death domain.
Handa N, Kukimoto-Niino M, Akasaka R, Murayama K, Terada T, Inoue M, Yabuki T, Aoki M, Seki E, Matsuda T, Nunokawa E, Tanaka A, Hayashizaki Y, Kigawa T, Shirouzu M, Yokoyama S
Acta Crystallogr D Biol Crystallogr 62 1502-9 (2006)
PMID: 17139086

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185055 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Netrin receptor UNC5B Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 103 amino acids
Theoretical weight: 11.2 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q8K1S3 (Residues: 854-943; Coverage: 10%)
Gene names: Unc5b, Unc5h2
Sequence domains: Death domain
Structure domains: Death Domain, Fas

Ligands and Environments

2 bound ligands:
Ligand SO3 7 x SO3
Ligand SO4 3 x SO4
1 modified residue:
Ligand MSE 24 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: C2
Unit cell:
a: 124.878Å b: 47.207Å c: 121.177Å
α: 90° β: 119.56° γ: 90°
R-values:
R R work R free
0.229 0.229 0.269
Expression system: Not provided

Quick links

Citations

1 review citation

Assembly of platforms for signal transduction in the new era: dimerization, helical filament assembly, and beyond.
Ha et al. (2020)
2 other articles

1 mention without citation

Analysis of the impact of solvent on contacts prediction in proteins.
Samsonov et al. (2009)