› 1wo9

Solution NMR

Selective inhibition of trypsins by insect peptides: role of P6-P10 loop

Released:
DOI: 10.2210/pdb1wo9/pdb
PDB entry 1wo9 coloured by chain, front view.
PDB entry 1wo9 coloured by chain, side view.
PDB entry 1wo9 coloured by chain, top view.
Source organism: Locusta migratoria migratorioides
Primary publication:
Selective inhibition of trypsins by insect peptides: role of P6-P10 loop.
Kellenberger C, Ferrat G, Leone P, Darbon H, Roussel A
Biochemistry 42 13605-12 (2003)
PMID: 14622007

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186677 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protease inhibitor Chain: A
Molecule details ›
Chain: A
Length: 35 amino acids
Theoretical weight: 3.73 KDa
Source organism: Locusta migratoria migratorioides
Expression system: Not provided
UniProt:
  • Canonical: Q8WQ22 (Residues: 23-57; Coverage: 29%)
Gene name: pp2
Sequence domains: Pacifastin inhibitor (LCMII)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

2 review citations

Molecular mechanisms of phase change in locusts.
Wang et al. (2014)
1 more

1 mention without citation

Insect protease inhibitors; promising inhibitory compounds against SARS-CoV-2 main protease.
Hemmati et al. (2022)