1ws4

X-ray diffraction
1.9Å resolution

Crystal structure of Jacalin- Me-alpha-Mannose complex: Promiscuity vs Specificity

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-148425 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Agglutinin alpha chain Chains: A, G
Molecule details ›
Chains: A, G
Length: 133 amino acids
Theoretical weight: 14.64 KDa
Source organism: Artocarpus integer
UniProt:
  • Canonical: P18670 (Residues: 1-133; Coverage: 100%)
Sequence domains: Jacalin-like lectin domain
Structure domains: Jacalin-like lectin domain
Agglutinin beta-3 chain Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 20 amino acids
Theoretical weight: 2.03 KDa
Source organism: Artocarpus integer
UniProt:
  • Canonical: P18673 (Residues: 1-20; Coverage: 100%)
Agglutinin alpha chain Chains: C, E
Molecule details ›
Chains: C, E
Length: 133 amino acids
Theoretical weight: 14.67 KDa
Source organism: Artocarpus integer
UniProt:
  • Canonical: P18670 (Residues: 1-133; Coverage: 100%)
Sequence domains: Jacalin-like lectin domain
Structure domains: Jacalin-like lectin domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 79.287Å b: 99.416Å c: 105.464Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.184 0.205