› 1wv6

X-ray diffraction
2.55Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114780 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*GP*CP*GP*TP*AP*(2BT)P*AP*CP*GP*C)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 3.12 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand SR 5 x SR
1 modified residue:
Ligand 2BT 2 x 2BT

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P41212
Unit cell:
a: 43.566Å b: 43.566Å c: 69.944Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.218 0.244
Expression system: Not provided

Quick links

Citations

15 review citations

The chemical evolution of oligonucleotide therapies of clinical utility.
Khvorova et al. (2017)
14 more

1 mention without citation

Structural variability of CG-rich DNA 18-mers accommodating double T-T mismatches.
Kolenko et al. (2020)