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Solution NMR

NMR Solution Structure of BmK-betaIT, an Excitatory Scorpion Toxin from Buthus martensi Karsch

Released:
DOI: 10.2210/pdb1wwn/pdb
PDB entry 1wwn coloured by chain, ensemble of 20 models, front view.
PDB entry 1wwn coloured by chain, ensemble of 20 models, side view.
PDB entry 1wwn coloured by chain, ensemble of 20 models, top view.
Source organism: Mesobuthus martensii
Primary publication:
NMR solution structure of BmK-betaIT, an excitatory scorpion beta-toxin without a 'hot spot' at the relevant position.
Tong X, Yao J, He F, Chen X, Zheng X, Xie C, Wu G, Zhang N, Ding J, Wu H
Biochem Biophys Res Commun 349 890-9 (2006)
PMID: 16970911

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130242 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-insect excitatory toxin BmKIT1 Chain: A
Molecule details ›
Chain: A
Length: 69 amino acids
Theoretical weight: 7.65 KDa
Source organism: Mesobuthus martensii
UniProt:
  • Canonical: O61668 (Residues: 19-87; Coverage: 99%)
Sequence domains: Scorpion toxin-like domain
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: The structure are based on a total of 884 constraints, 814 are NOE-derived distance constraints,26 dihedral angle constraints,44 distance constraints from sixteen hydrogen bonds and four disulfide bonds.

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Citations

1 review citation

Arthropod venoms: a vast arsenal of insecticidal neuropeptides.
Schwartz et al. (2012)
4 other articles