› 1wwy

Solution NMR

Solution structure of the DUF1000 domain of a thioredoxin-like protein 1

Released:
DOI: 10.2210/pdb1wwy/pdb
PDB entry 1wwy coloured by chain, ensemble of 20 models, front view.
PDB entry 1wwy coloured by chain, ensemble of 20 models, side view.
PDB entry 1wwy coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein.
Goroncy AK, Koshiba S, Tochio N, Tomizawa T, Inoue M, Tanaka A, Sugano S, Kigawa T, Yokoyama S
Proteins 78 2176-80 (2010)
PMID: 20455272

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128915 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 19.08 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O43396 (Residues: 122-279; Coverage: 55%)
Gene names: TRP32, TXL, TXNL, TXNL1
Sequence domains: PITH domain
Structure domains: PITH domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

2 review citations

The role of TXNL1 in disease: treatment strategies for cancer and diseases with oxidative stress.
Zhao et al. (2021)
1 more

2 mentions without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)
1 more