› 1wz3

X-ray diffraction
1.8Å resolution

The crystal structure of plant ATG12

Released:
DOI: 10.2210/pdb1wz3/pdb
PDB entry 1wz3 coloured by chain, front view.
PDB entry 1wz3 coloured by chain, side view.
PDB entry 1wz3 coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
The crystal structure of plant ATG12 and its biological implication in autophagy.
Suzuki NN, Yoshimoto K, Fujioka Y, Ohsumi Y, Inagaki F
Autophagy 1 119-26 (2005)
PMID: 16874047

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192330 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin-like protein ATG12B Chains: A, B
Molecule details ›
Chains: A, B
Length: 96 amino acids
Theoretical weight: 10.52 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9LVK3 (Residues: 1-94; Coverage: 100%)
Gene names: APG12, APG12B, ATG12B, At3g13970, MDC16.9
Sequence domains: Ubiquitin-like autophagy protein Apg12
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 44.693Å b: 38.264Å c: 52.511Å
α: 90° β: 98.87° γ: 90°
R-values:
R R work R free
0.221 0.219 0.242
Expression system: Escherichia coli

Quick links

Citations

28 review citations

Autophagosome formation: core machinery and adaptations.
Xie et al. (2007)
27 more

8 mentions without citation

The natural history of ubiquitin and ubiquitin-related domains.
Burroughs et al. (2012)
7 more