Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Protein tyrosine phosphatase type IVA 1 (preferred)
PDBe Complex ID:
PDB-CPX-181227 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein tyrosine phosphatase type IVA 1
Molecule details ›
Chains: A, B
Length: 180 amino acids
Theoretical weight: 20.54 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Dual specificity phosphatase, catalytic domain
Structure domains: Protein tyrosine phosphatase superfamily
Length: 180 amino acids
Theoretical weight: 20.54 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q78EG7 (Residues: 1-160; Coverage: 93%)
Sequence domains: Dual specificity phosphatase, catalytic domain
Structure domains: Protein tyrosine phosphatase superfamily
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X9A
Spacegroup:
I213
Expression system: Escherichia coli BL21
