› 1x6o

X-ray diffraction
1.6Å resolution

Structural Analysis of Leishmania braziliensis eukaryotic initiation factor 5a

Released:
DOI: 10.2210/pdb1x6o/pdb
PDB entry 1x6o coloured by chain, front view.
PDB entry 1x6o coloured by chain, side view.
PDB entry 1x6o coloured by chain, top view.
Source organism: Leishmania braziliensis
Entry authors: Bosch J, Robien MA, Hol WGJ, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107312 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 5A Chain: A
Molecule details ›
Chain: A
Length: 174 amino acids
Theoretical weight: 18.86 KDa
Source organism: Leishmania braziliensis
Expression system: Escherichia coli
UniProt:
  • Canonical: A4HE05 (Residues: 1-166; Coverage: 100%)
Gene names: EIF5A1, EIF5A2, LBRM_25_0580, LBRM_25_0590, LBRM_25_0600, LBRM_25_0610
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2, SSRL BEAMLINE BL9-1
Spacegroup: P3221
Unit cell:
a: 64.991Å b: 64.991Å c: 88.297Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.174 0.214
Expression system: Escherichia coli

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