› 1xak

X-ray diffraction
1.8Å resolution

STRUCTURE OF THE SARS-CORONAVIRUS ORF7A ACCESSORY PROTEIN

Released:
DOI: 10.2210/pdb1xak/pdb
PDB entry 1xak coloured by chain, front view.
PDB entry 1xak coloured by chain, side view.
PDB entry 1xak coloured by chain, top view.
Source organism: Severe acute respiratory syndrome-related coronavirus
Primary publication:
Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein.
Nelson CA, Pekosz A, Lee CA, Diamond MS, Fremont DH
Structure 13 75-85 (2005)
PMID: 15642263

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157828 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ORF7a protein Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 9.42 KDa
Source organism: Severe acute respiratory syndrome-related coronavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: P59635 (Residues: 14-96; Coverage: 76%)
Gene name: 7a
Sequence domains: Betacoronavirus NS7A protein
Structure domains: SARS coronavirus X4

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-D
Spacegroup: P31
Unit cell:
a: 37.1Å b: 37.1Å c: 55.33Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.223 0.223 0.275
Expression system: Escherichia coli

Quick links

Citations

20 review citations

Nidovirales: evolving the largest RNA virus genome.
Gorbalenya et al. (2006)
19 more

22 mentions without citation

COVID-19 Outbreak: An Overview.
Ciotti et al. (2019)
21 more