› 1xbs

X-ray diffraction
2.5Å resolution

Crystal structure of human dim2: a dim1-like protein

Released:
DOI: 10.2210/pdb1xbs/pdb
PDB entry 1xbs coloured by chain, front view.
PDB entry 1xbs coloured by chain, side view.
PDB entry 1xbs coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Biochemical characterization and crystal structure of a Dim1 family associated protein: Dim2.
Simeoni F, Arvai A, Bello P, Gondeau C, Hopfner KP, Neyroz P, Heitz F, Tainer J, Divita G
Biochemistry 44 11997-2008 (2005)
PMID: 16142897

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192672 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin-like protein 4B Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 17.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NX01 (Residues: 1-149; Coverage: 100%)
Gene names: DIM2, DLP, TXNL4B
Sequence domains: Mitosis protein DIM1
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P41212
Unit cell:
a: 78.16Å b: 78.16Å c: 60.334Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.324 0.242 0.305
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Development of protein mimics for intracellular delivery.
deRonde et al. (2015)
1 more

1 mention without citation

High-resolution crystal structure of human Dim2/TXNL4B.
Jin et al. (2013)