› 1xci

Solution NMR

Mispair Aligned N3T-Butyl-N3T Interstrand Crosslink

Released:
DOI: 10.2210/pdb1xci/pdb
PDB entry 1xci coloured by chain, front view.
PDB entry 1xci coloured by chain, side view.
PDB entry 1xci coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Intrastrand base-stacking buttresses widening of major groove in interstrand cross-linked B-DNA.
da Silva MW, Bierbryer RG, Wilds CJ, Noronha AM, Colvin OM, Miller PS, Gamcsik MP
Bioorg Med Chem 13 4580-7 (2005)
PMID: 15953553

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114806 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*GP*AP*AP*AP*(TTM)P*TP*TP*TP*CP*G)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 11 nucleotides
Theoretical weight: 3.38 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand TTM 2 x TTM

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing, molecular dynamics
Expression system: Not provided

Quick links

Citations

2 citation in other articles

Sequence-dependent nanometer-scale conformational dynamics of individual RecBCD-DNA complexes.
Carter et al. (2016)
1 more

1 mention without citation

First principles effective electronic couplings for hole transfer in natural and size-expanded DNA.
Migliore et al. (2009)