Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Hydrolysis of four peptide bonds in the viral precursor polyprotein, commonly with Asp or Glu in the P6 position, Cys or Thr in P1 and Ser or Ala in P1'.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-210915 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Mature core protein
Molecule details ›
Chains: P, Q
Length: 44 amino acids
Theoretical weight: 4.91 KDa
Source organism: Hepatitis C virus isolate HC-J8
Expression system: Not provided
UniProt:
Length: 44 amino acids
Theoretical weight: 4.91 KDa
Source organism: Hepatitis C virus isolate HC-J8
Expression system: Not provided
UniProt:
- Canonical:
P26661 (Residues: 2-45; Coverage: 2%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-2
Spacegroup:
P21212
Expression systems:
- Not provided
- Escherichia coli
