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› 1xfo

X-ray diffraction
1.96Å resolution

Crystal Structure of an archaeal aminopeptidase

Released:
DOI: 10.2210/pdb1xfo/pdb
Model geometry
Fit model/data
PDB entry 1xfo coloured by chain, front view.
PDB entry 1xfo coloured by chain, side view.
PDB entry 1xfo coloured by chain, top view.
Source organism: Pyrococcus horikoshii
Primary publication:
Crystal structure of a dodecameric tetrahedral-shaped aminopeptidase.
Russo S, Baumann U
J Biol Chem 279 51275-81 (2004)
PMID: 15375159

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129829 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tetrahedral aminopeptidase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 357 amino acids
Theoretical weight: 39.51 KDa
Source organism: Pyrococcus horikoshii
Expression system: Escherichia coli
UniProt:
  • Canonical: O59196 (Residues: 1-353; Coverage: 100%)
Gene names: PH1527, frvX
Sequence domains: M42 glutamyl aminopeptidase
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 8 x ZN
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P63
Unit cell:
a: 158.34Å b: 158.34Å c: 114.46Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.183 0.183 0.209
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Haloarchaeal proteases and proteolytic systems.
De Castro et al. (2006)
1 more

3 mentions without citation

Structure of the dodecamer of the aminopeptidase APDkam598 from the archaeon Desulfurococcus kamchatkensis.
Petrova et al. (2015)
2 more