1xiq

X-ray diffraction
3.05Å resolution

Plasmodium falciparum Nucleoside diphosphate kinase B

Released:
Source organism: Plasmodium falciparum 3D7
Entry authors: Robien MA, Bosch J, Hol WGJ, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Function and Biology Details

Reaction catalysed:
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
PDBe Complex ID:
PDB-CPX-184740 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoside diphosphate kinase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 157 amino acids
Theoretical weight: 18.07 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8ID43 (Residues: 1-149; Coverage: 100%)
Gene name: PF3D7_1366500
Sequence domains: Nucleoside diphosphate kinase
Structure domains: Nucleoside diphosphate kinase-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21
Unit cell:
a: 68.593Å b: 112.424Å c: 68.59Å
α: 90° β: 119.05° γ: 90°
R-values:
R R work R free
0.232 0.229 0.286
Expression system: Escherichia coli