› 1xkq

X-ray diffraction
2.1Å resolution

Crystal Structure of Short-Chain Dehydrogenase/Reductase of unknown Function from Caenorhabditis Elegans with Cofactor

Released:
DOI: 10.2210/pdb1xkq/pdb
PDB entry 1xkq coloured by chain, front view.
PDB entry 1xkq coloured by chain, side view.
PDB entry 1xkq coloured by chain, top view.
Source organism: Caenorhabditis elegans
Entry authors: Schormann N, Zhou J, Karpova E, Zhang Y, Symersky J, Bunzel B, Huang W-Y, Arabshahi A, Qiu S, Luan C-H, Gray R, Carson M, Tsao J, Luo M, Johnson D, Lu S, Lin G, Luo D, Cao Z, Li S, McKinstry A, Shang Q, Chen Y-J, Bray T, Nagy L, DeLucas L, Southeast Collaboratory for Structural Genomics (SECSG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192406 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DeHydrogenases, Short chain Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 280 amino acids
Theoretical weight: 29.95 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9N5G4 (Residues: 1-280; Coverage: 100%)
Gene names: CELE_R05D8.7, R05D8.7
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

1 bound ligand:
Ligand NDP 4 x NDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-3
Spacegroup: P61
Unit cell:
a: 119.69Å b: 119.69Å c: 193.22Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.216 0.245
Expression system: Escherichia coli BL21(DE3)

Quick links