› 1xm9

X-ray diffraction
2.8Å resolution

Structure of the armadillo repeat domain of plakophilin 1

Released:
DOI: 10.2210/pdb1xm9/pdb
PDB entry 1xm9 coloured by chain, front view.
PDB entry 1xm9 coloured by chain, side view.
PDB entry 1xm9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the armadillo repeat domain of plakophilin 1.
Choi HJ, Weis WI
J Mol Biol 346 367-76 (2005)
PMID: 15663951

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171823 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plakophilin-1 Chain: A
Molecule details ›
Chain: A
Length: 457 amino acids
Theoretical weight: 50.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q13835 (Residues: 244-721; Coverage: 61%)
Gene name: PKP1
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: C2221
Unit cell:
a: 53.355Å b: 131.977Å c: 142.044Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.255 0.255 0.324
Expression system: Escherichia coli BL21

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Citations

26 review citations

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Garrod et al. (2008)
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8 mentions without citation

Mechanistic basis of desmosome-targeted diseases.
Al-Jassar et al. (2013)
7 more