› 1xop

Solution NMR

NMR structure of G1V mutant of influenza hemagglutinin fusion peptide in DPC micelles at pH 5

Released:
DOI: 10.2210/pdb1xop/pdb
PDB entry 1xop coloured by chain, ensemble of 25 models, front view.
PDB entry 1xop coloured by chain, ensemble of 25 models, side view.
PDB entry 1xop coloured by chain, ensemble of 25 models, top view.
Source organism: Influenza A virus (A/Netherlands/284/03(H7N7))
Primary publication:
Membrane structures of the hemifusion-inducing fusion peptide mutant G1S and the fusion-blocking mutant G1V of influenza virus hemagglutinin suggest a mechanism for pore opening in membrane fusion.
Li Y, Han X, Lai AL, Bushweller JH, Cafiso DS, Tamm LK
J Virol 79 12065-76 (2005)
PMID: 16140782

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180461 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hemagglutinin Chain: A
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 2.1 KDa
Source organism: Influenza A virus (A/Netherlands/284/03(H7N7))
Expression system: Not provided
UniProt:
  • Canonical: Q6VMJ8 (Residues: 84-102; Coverage: 17%)
Gene name: HA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

8 review citations

Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme.
White et al. (2008)
7 more

6 mentions without citation

Photochemistry of flavoprotein light sensors.
Conrad et al. (2014)
5 more