› 1xrh

X-ray diffraction
2.25Å resolution

Crystal Structure of Ureidoglycolate Dehydrogenase from Escherichia Coli

Released:
DOI: 10.2210/pdb1xrh/pdb
PDB entry 1xrh coloured by chain, front view.
PDB entry 1xrh coloured by chain, side view.
PDB entry 1xrh coloured by chain, top view.
Source organism: Escherichia coli
Entry authors: Rajashankar KR, Kniewel R, Lima CD, Burley SK, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
(S)-ureidoglycolate + NAD(+) = N-carbamoyl-2-oxoglycine + NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160181 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ureidoglycolate dehydrogenase (NAD(+)) Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 351 amino acids
Theoretical weight: 38.7 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P77555 (Residues: 2-349; Coverage: 100%)
Gene names: JW0505, allD, b0517, glxB8, ylbC
Sequence domains: Malate/L-lactate dehydrogenase
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 96 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P21
Unit cell:
a: 104.715Å b: 129.916Å c: 106.468Å
α: 90° β: 95.77° γ: 90°
R-values:
R R work R free
0.192 0.192 0.25
Expression system: Escherichia coli

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