› 1xu0

Solution NMR

Solution structure of Xenopus leavis prion protein

Released:
DOI: 10.2210/pdb1xu0/pdb
PDB entry 1xu0 coloured by chain, ensemble of 20 models, front view.
PDB entry 1xu0 coloured by chain, ensemble of 20 models, side view.
PDB entry 1xu0 coloured by chain, ensemble of 20 models, top view.
Source organism: Xenopus laevis
Primary publication:
Prion protein NMR structures of chickens, turtles, and frogs.
Calzolai L, Lysek DA, Pérez DR, Güntert P, Wüthrich K
Proc Natl Acad Sci U S A 102 651-5 (2005)
PMID: 15647366

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177797 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prion/Doppel protein beta-ribbon domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 15.02 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q5S1W7 (Residues: 43-171; Coverage: 75%)
Sequence domains: Prion/Doppel alpha-helical domain
Structure domains: Prion/Doppel protein, beta-ribbon domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21

Quick links

Citations

21 review citations

Physiology of the prion protein.
Linden et al. (2008)
20 more

10 mentions without citation

A structural overview of the vertebrate prion proteins.
Pastore et al. (2007)
9 more