› 1xu2

X-ray diffraction
2.35Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169691 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tumor necrosis factor ligand superfamily member 13 Chains: A, B, D
Molecule details ›
Chains: A, B, D
Length: 138 amino acids
Theoretical weight: 15.56 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9D777 (Residues: 104-241; Coverage: 57%)
Gene names: April, Tnfsf13
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls
Tumor necrosis factor receptor superfamily member 17 Chains: R, S, T
Molecule details ›
Chains: R, S, T
Length: 47 amino acids
Theoretical weight: 5.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q02223 (Residues: 5-51; Coverage: 26%)
Gene names: BCM, BCMA, TNFRSF17
Sequence domains: BCMA, TALL-1 binding

Ligands and Environments

1 bound ligand:
Ligand NI 1 x NI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P61
Unit cell:
a: 114.294Å b: 114.294Å c: 91.18Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.182 0.178 0.213
Expression system: Escherichia coli

Quick links

Citations

31 review citations

Cracking the BAFF code.
Mackay et al. (2009)
30 more

17 mentions without citation

Cytokines and Production of Aberrantly O-Glycosylated IgA1, the Main Autoantigen in IgA Nephropathy.
Person et al. (2022)
16 more