› 1xv2

X-ray diffraction
2Å resolution

Crystal Structure of a Protein of Unknown Function Similar to Alpha-acetolactate Decarboxylase from Staphylococcus aureus

Released:
DOI: 10.2210/pdb1xv2/pdb
PDB entry 1xv2 coloured by chain, front view.
PDB entry 1xv2 coloured by chain, side view.
PDB entry 1xv2 coloured by chain, top view.
Source organism: Staphylococcus aureus
Entry authors: Duke NEC, Zhang R, Quartey P, Collart F, Holzle D, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Reaction catalysed: 
(2S)-2-hydroxy-2-methyl-3-oxobutanoate = (3R)-3-hydroxybutan-2-one + CO(2)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101949 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-acetolactate decarboxylase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 237 amino acids
Theoretical weight: 26.99 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0H3JS15 (Residues: 1-234; Coverage: 100%)
Gene name: SA2394
Sequence domains: Alpha-acetolactate decarboxylase
Structure domains: Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
1 modified residue:
Ligand MSE 24 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 48.434Å b: 160.005Å c: 68.056Å
α: 90° β: 107.55° γ: 90°
R-values:
R R work R free
0.191 0.191 0.236
Expression system: Escherichia coli BL21(DE3)

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