› 1xwc

X-ray diffraction
2.3Å resolution

Drosophila thioredoxin, reduced, P6522

Released:
DOI: 10.2210/pdb1xwc/pdb
PDB entry 1xwc coloured by chain, front view.
PDB entry 1xwc coloured by chain, side view.
PDB entry 1xwc coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster.
Wahl MC, Irmler A, Hecker B, Schirmer RH, Becker K
J Mol Biol 345 1119-30 (2005)
PMID: 15644209

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194195 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin-2 Chain: A
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 11.75 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9V429 (Residues: 1-106; Coverage: 100%)
Gene names: CG31884, Trx-2
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P6522
Unit cell:
a: 52.954Å b: 52.954Å c: 152.939Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.221 0.221 0.249
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Reactivity of thioredoxin as a protein thiol-disulfide oxidoreductase.
Cheng et al. (2011)
1 more

3 mentions without citation

Unifying mechanical and thermodynamic descriptions across the thioredoxin protein family.
Mottonen et al. (2009)
2 more