Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- P-loop containing nucleoside triphosphate hydrolase
- ClpA/B family
- DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
- DNA polymerase III, gamma subunit, domain III
- DNA polymerase III, subunit gamma/tau, helical lid domain
- AAA+ ATPase domain
- DNA polymerase III, subunit gamma/ tau, N-terminal
- DNA polymerase III, delta subunit, C-terminal
4 more domains
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
DNA polymerase III (preferred)
PDBe Complex ID:
PDB-CPX-139153 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
DNA polymerase III subunit delta
Molecule details ›
Chains: A, F
Length: 343 amino acids
Theoretical weight: 38.75 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 343 amino acids
Theoretical weight: 38.75 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P28630 (Residues: 1-343; Coverage: 100%)
Sequence domains:
DNA polymerase III subunit tau
Molecule details ›
DNA polymerase III subunit delta'
Molecule details ›
Chains: E, J
Length: 334 amino acids
Theoretical weight: 36.98 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 334 amino acids
Theoretical weight: 36.98 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P28631 (Residues: 1-334; Coverage: 100%)
Sequence domains:
