› 1xzo

X-ray diffraction
1.7Å resolution

Identification of a disulfide switch in BsSco, a member of the Sco family of cytochrome c oxidase assembly proteins

Released:
DOI: 10.2210/pdb1xzo/pdb
PDB entry 1xzo coloured by chain, front view.
PDB entry 1xzo coloured by chain, side view.
PDB entry 1xzo coloured by chain, top view.
Source organism: Bacillus subtilis
Primary publication:
Identification of a disulfide switch in BsSco, a member of the Sco family of cytochrome c oxidase assembly proteins.
Ye Q, Imriskova-Sosova I, Hill BC, Jia Z
Biochemistry 44 2934-42 (2005)
PMID: 15723536

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-156957 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SCO1 protein homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 174 amino acids
Theoretical weight: 19.75 KDa
Source organism: Bacillus subtilis
Expression system: Escherichia coli
UniProt:
  • Canonical: P54178 (Residues: 20-193; Coverage: 99%)
Gene names: BSU21750, ypmQ
Sequence domains: SCO1/SenC
Structure domains: Glutaredoxin

Ligands and Environments

2 bound ligands:
Ligand CD 5 x CD
Ligand CA 14 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: P3221
Unit cell:
a: 68.033Å b: 68.033Å c: 191.733Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.241 0.238 0.289
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Assembly of mitochondrial cytochrome c-oxidase, a complicated and highly regulated cellular process.
Fontanesi et al. (2006)
7 more

8 mentions without citation

The CD1 size problem: lipid antigens, ligands, and scaffolds.
Ly et al. (2014)
7 more