› 1y0h

X-ray diffraction
1.6Å resolution

Structure of Rv0793 from Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb1y0h/pdb
PDB entry 1y0h coloured by chain, front view.
PDB entry 1y0h coloured by chain, side view.
PDB entry 1y0h coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
The crystal structure of Rv0793, a hypothetical monooxygenase from M. tuberculosis.
Lemieux MJ, Ference C, Cherney MM, Wang M, Garen C, James MN
J Struct Funct Genomics 6 245-57 (2005)
PMID: 16496224

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131470 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative monooxygenase Rv0793 Chains: A, B
Molecule details ›
Chains: A, B
Length: 102 amino acids
Theoretical weight: 11.26 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: O86332 (Residues: 1-101; Coverage: 100%)
Gene name: Rv0793
Sequence domains: Antibiotic biosynthesis monooxygenase
Structure domains: Alpha-Beta Plaits

Ligands and Environments

1 bound ligand:
Ligand ACT 3 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P1
Unit cell:
a: 30.44Å b: 34.6Å c: 42.85Å
α: 103.44° β: 107.96° γ: 94.34°
R-values:
R R work R free
0.176 0.173 0.219
Expression system: Escherichia coli

Quick links

Citations

7 citation in other articles

Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa.
Yang et al. (2016)
6 more

1 mention without citation

Two novel classes of enzymes are required for the biosynthesis of aurofusarin in Fusarium graminearum.
Frandsen et al. (2011)