› 1y8l

X-ray diffraction
1.5Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114845 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*GP*CP*GP*TP*AP*(TFE)P*AP*CP*GP*C)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 3.14 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand SPM 1 x SPM
1 modified residue:
Ligand TFE 2 x TFE

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 24.636Å b: 45.02Å c: 45.132Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.171 0.202
Expression system: Not provided

Quick links

Citations

15 review citations

The chemical evolution of oligonucleotide therapies of clinical utility.
Khvorova et al. (2017)
14 more