› 1ycw

Solution NMR

Clustered abasic lesions in dna: nmr solution structures of clustered bistranded-1 abasic lesion

Released:
DOI: 10.2210/pdb1ycw/pdb
PDB entry 1ycw coloured by chain, ensemble of 5 models, front view.
PDB entry 1ycw coloured by chain, ensemble of 5 models, side view.
PDB entry 1ycw coloured by chain, ensemble of 5 models, top view.
Source organism: Synthetic construct
Primary publication:
NMR solution structures of bistranded abasic site lesions in DNA.
Hazel RD, Tian K, de Los Santos C
Biochemistry 47 11909-19 (2008)
PMID: 18950195

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114858 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(*CP*GP*CP*AP*TP*GP*(3DR)P*GP*TP*AP*CP*GP*C)-3' Chain: A
Molecule details ›
Chain: A
Length: 13 nucleotides
Theoretical weight: 3.84 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(*GP*CP*GP*TP*AP*CP*CP*(3DR)P*AP*TP*GP*CP*G)-3' Chain: B
Molecule details ›
Chain: B
Length: 13 nucleotides
Theoretical weight: 3.84 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RESTRAINED MOLECULAR DYNAMICS
Expression system: Not provided

Quick links

Citations

2 review citations

Induction and repair of clustered DNA lesions: what do we know so far?
Georgakilas et al. (2013)
1 more

2 mentions without citation

Impact of bistrand abasic sites and proximate orientation on DNA global structure and duplex energetics.
Minetti et al. (2018)
1 more