› 1ys5

Solution NMR

Solution structure of the antigenic domain of GNA1870 of Neisseria meningitidis

Released:
DOI: 10.2210/pdb1ys5/pdb
PDB entry 1ys5 coloured by chain, ensemble of 30 models, front view.
PDB entry 1ys5 coloured by chain, ensemble of 30 models, side view.
PDB entry 1ys5 coloured by chain, ensemble of 30 models, top view.
Source organism: Neisseria meningitidis
Primary publication:
Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis.
Cantini F, Savino S, Scarselli M, Masignani V, Pizza M, Romagnoli G, Swennen E, Veggi D, Banci L, Rappuoli R
J Biol Chem 281 7220-7 (2006)
PMID: 16407174

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191680 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Factor H binding protein Chain: A
Molecule details ›
Chain: A
Length: 164 amino acids
Theoretical weight: 17.63 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9JXV4 (Residues: 120-274; Coverage: 61%)
Gene names: NMB1870, fhbP
Sequence domains: Factor H binding protein, C-terminal
Structure domains: Porin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

Vaccinology in the genome era.
Rinaudo et al. (2009)
7 more

1 mention without citation

Structure of the uncomplexed Neisseria meningitidis factor H-binding protein fHbp (rLP2086).
Cendron et al. (2011)